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P-Shot (Regenerative PRP)

Clinical Lead

Meva Clinic Clinical Care Team

Meva Clinic · Istanbul
Published: 2025-11-12
Last Updated: 2026-05-18

P-Shot (Regenerative PRP)

Designed to support sexual wellness and sensitivity using growth factors from your own blood. Results vary by patient and require doctor assessment.

Meva Clinic Clinical Care Team

Patient Care Information

Patient Care Information

"Our clinical approach prioritizes patient safety, individualized treatment planning, realistic expectations, and long-term follow-up throughout the international care journey."

About This Procedure

Why Choose Meva Clinic?

Designed to support sexual wellness and sensitivity using growth factors from your own blood. Results vary by patient and require doctor assessment.

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Patient Care Information

Meva Clinic Clinical Care Team

Clinical Governance & Specialist Pathway Standards

This content is maintained by Meva Clinic’s Clinical Care Team for patient guidance and clinical transparency. Final treatment suitability, operating physician assignment, surgical planning, and medical decisions are confirmed only after medical history review, in-person consultation, diagnostic tests, anesthesia evaluation, and doctor availability.

Meva Clinic Clinical Care

Is This Treatment for Me?

Changes in erection quality

Reduced sensitivity

Seeking a non-surgical regenerative option

Comprehensive International Patient Care Plan

Private airport transfer according to the confirmed care plan

Bosphorus-view partner hotel, according to the confirmed care plan

Dedicated patient support during the confirmed care pathway

Aftercare guidance or materials according to the confirmed treatment plan

Follow-up guidance according to individual medical recommendations

The Clinical Procedure

Concentrated platelet injection.

1

Medical Assessment

The doctor reviews your medical history, medications and concerns; possible underlying causes of erection changes are considered before PRP is recommended.

2

PRP Preparation

A small blood sample is taken and processed in a centrifuge to concentrate the platelets from your own blood.

3

Injection

After a numbing cream has taken effect, the PRP is injected into selected areas of the penis with a fine needle.

4

Aftercare Review

The area is checked, aftercare instructions are explained, and whether further sessions are advisable is discussed.

Recovery & Transformation Journey

1

Phase 1: Direct Rest

Avoid direct friction or pressure on the injection sites. Mild swelling or bruising is normal.

2

Phase 2: Activity Caution

Resume light daily activities. Avoid intense exercises or gym/swimming for 2–3 days.

3

Phase 3: Sexual Abstinence

Abstain from sexual intercourse, masturbation, and friction to prevent discomfort or irritation (2–3 days).

4

Phase 4: Settled Results

Tissues heal completely. Sexual activity and sports may be resumed after doctor review.

The Meva Advantage

Double-spin centrifugation to prepare platelet-rich plasma.

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15+ Years Experience
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Clinical Standards & Safety

Medical Guidelines & Safety Protocols

Treatment pathways are coordinated with selected specialist medical partners and accredited provider institutions, depending on the procedure and doctor assessment. Below are the clinical guidelines, safety protocols, and medical reference documentation for this procedure.

Indicated / Suitable For

  • Men with mild changes in erection quality or penile sensitivity who have had a medical review and want to explore a regenerative, non-surgical option.
  • Men whose possible underlying causes, such as diabetes, cardiovascular risk factors or low testosterone, have been checked and addressed first.
  • Men who understand that the evidence for PRP in erectile problems is still limited and that responses vary from one man to another.
  • Men who prefer an outpatient treatment with a numbing cream, no hospital stay and a short stay of about two hotel nights in Istanbul.
  • Men who see PRP as one part of a care plan, used alongside the standard treatments their doctor recommends rather than instead of them.

Contraindications / Not Suitable

  • Low platelet counts, platelet function disorders or other blood disorders that affect clotting.
  • Anticoagulant or antiplatelet medication that cannot be safely paused or adjusted; any change is decided with the prescribing doctor, never alone.
  • Active infection, skin lesions or inflammation in the genital area, or a fever on the day of treatment.
  • Active cancer, particularly blood cancers, or ongoing chemotherapy, where growth-factor treatments are postponed or avoided.
  • Severe or clearly organic erectile dysfunction, where other options such as shockwave therapy, tablets or a penile prosthesis are more appropriate.

Pre-Operative Evaluation & Diagnostic Checks

1

Confidential Sexual Health Consultation: Review of changes in erection and sensitivity, their duration and context, often supported by a validated questionnaire such as the IIEF-5.

2

Medication and Medical History Review: Check of anticoagulants, antiplatelet drugs, erection tablets, previous treatments and conditions such as diabetes or high blood pressure.

3

Blood Tests: Full blood count including platelets, with blood sugar (HbA1c) and hormone levels such as testosterone where indicated.

4

Genital Examination: Assessment of the penile skin and tissue, including checks for curvature, plaques or signs of infection before injection.

Potential Risks & Complications

In compliance with transparent clinical reporting, Meva Clinic ensures patients are fully informed of the physiological risks associated with surgical procedures through accredited partner-hospital safety protocols where clinically appropriate.

Bruising and Small Haematoma

Minor bleeding at the injection sites is the most common effect; fine needles, gentle pressure afterwards and avoiding friction help it settle within days.

Discomfort and Tenderness

Brief stinging or pressure during injection and mild tenderness for a few days; the numbing cream and simple pain relief usually keep this manageable.

Swelling

Mild temporary swelling of the penile skin can occur; it normally resolves on its own, and sexual activity pauses for 2–3 days to let the tissues settle.

Infection

Uncommon when the blood is processed and injected under sterile conditions; redness, warmth, discharge or fever should be reported to the coordinator straight away.

Nodules or Plaque Formation

Isolated cases of small firm areas have been reported in studies; any lump is assessed at follow-up.

Limited or No Benefit

Recent meta-analyses of randomised trials show inconsistent results versus placebo, so some men notice little or no change; this is discussed openly before treatment.

Realistic Expectations & Outcomes

The P-Shot uses your own platelets to support penile tissue, but it is not a cure for erectile dysfunction and does not treat its underlying cause. Randomised trials so far are small and their results are mixed: some men notice firmer erections or better sensitivity, while others notice little change. Any effect develops gradually over weeks rather than immediately, and mild swelling or bruising in the first days says nothing about the final result. The response is usually judged after several weeks to a few months, when the doctor reviews how you feel and whether further sessions make sense. Tablets or other treatments may still be needed.

Revision & Follow-Up Policy

Follow-up continues remotely through your coordinator, with check-ins at around 1, 3 and 6 months to review erection quality, sensitivity and any side effects. If the response is limited, the doctor may discuss whether additional PRP sessions are reasonable or whether another approach, such as shockwave therapy or medication, would suit you better. Any further session is planned individually after assessment and is never automatic. For 12 months after your treatment you can also send photos to the medical team whenever you wish and receive their feedback, and your questions are answered remotely.

Authoritative Medical References & Studies

  • [1]
    de Amorim LGCR, Sanches MR, Pereira TA, et al. Efficacy of platelet-rich therapies versus placebo in the treatment of erectile dysfunction: an updated systematic review and meta-analysis of randomized controlled trials. J Sex Med. 2026;23(3).View Source
  • [2]
    Jacob D, Hay J, Rahemtoola MS, et al. Current advances in platelet-rich plasma therapy for erectile dysfunction: a meta-analysis of randomized controlled trials. J Sex Med. 2026;23(1).View Source
  • [3]
    Kohn T, El-Sakka A, Facio F, et al. Systematic review on the safety and effectiveness of restorative therapies for erectile dysfunction. J Sex Med. 2026;23(7).View Source

Medical Disclaimer: This information is educational and does not replace a medical consultation. PRP for erectile problems is still under investigation, and suitability, protocol and the number of sessions are decided only after a confidential review of your history, medications and blood tests by the treating doctor.

Frequently Asked Questions

A numbing cream is applied beforehand to reduce discomfort. You may still feel brief pressure or stinging during the injections; tolerance varies, and mild tenderness or bruising can last a few days.
No. The P-shot is not a size treatment, and no controlled study has shown a lasting increase in length or girth. Some men notice temporary fullness in the first days, but this is swelling from the injections and fades as the tissue settles. The treatment aims at erection quality and sensitivity only. If size is your main concern, tell your coordinator, and the doctor can explain which procedures are actually designed for that.
The evidence is weak. In published studies, a 2026 meta-analysis of 7 randomised trials with 479 men found no difference between PRP and placebo in erectile-function scores at 1, 3 and 6 months, and a second review of 7 trials (512 men) found no consistent, clinically meaningful benefit. Some men still report firmer erections, but results are unpredictable, so the P-shot should be seen as an experimental option, not a proven cure.
Nobody can say reliably. The randomised trials published so far followed men for only about 6 months, so there are no solid data on longer-term effects. Men who notice an improvement may find it fades over time, and some notice no change at all. Your coordinator checks in at around 1, 3 and 6 months, and the doctor reviews whether a further session makes sense or another approach would suit you better.
Because the plasma comes from your own blood, there is no risk of allergy or rejection to the substance itself. In published studies, PRP injections were well tolerated, with only isolated mild side effects such as small haematomas and plaque formation reported. Bruising, tenderness and brief swelling are the usual effects. It is not suitable for men with platelet or other blood disorders, so your medical history and medicines are reviewed before treatment.
There is no agreed protocol. In published randomised trials, men received between 2 and 4 sessions. Many men start with one session and decide on any further treatment only after the doctor has reviewed the response at follow-up. If more than one session is recommended, the doctor sets the interval, so sessions are usually planned as separate visits rather than packed into one trip. Nothing is added automatically.
Usually two hotel nights. There is no hospital stay: a small blood sample is taken, processed in a centrifuge and injected after a numbing cream has taken effect, all in one outpatient appointment. You can return to everyday activities and desk work straight away. Sexual activity, the gym and swimming pause for 2–3 days, and flying home after the second night is generally fine.
Often, yes. The P-shot does not replace tablets, and men who use them may still need them afterwards. Combining PRP with other treatments has not been well studied, so any combination is decided individually by the doctor. If tests suggest that reduced blood flow is the main cause of your erectile problems, shockwave therapy may be discussed as an alternative or an addition.
Yes. Your enquiry, medical history and photos are handled confidentially from the first message and shared only with the medical team involved in your care. You choose how and when your coordinator contacts you, and nothing is shared with anyone else without your consent. The appointment itself is short and outpatient, with no hospital admission, and any bruising is not visible under everyday clothing.

Procedure Details

Hospital Stay

None

Hotel Package

2 Nights

Return to Work

Immediate

Anaesthesia

Topical

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Medical Disclaimer: The clinical information on this website is for educational and informational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified physician or healthcare provider regarding any medical condition or surgical procedure in Turkey.

Airport transfers are included in the confirmed package; partner-hotel stays are optional, on request (separate cost).

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