Clinical Lead
Meva Clinic Bariatric Care Team
Gastric Botox Injection
- no surgery
- endoscopic procedure
- written quote in 24h
- English-speaking coordinator
A non-surgical endoscopic procedure that temporarily slows stomach emptying and supports appetite control in eligible patients, as part of a nutrition plan.
Meva Clinic Bariatric Care Team
Patient Care Information
Patient Care Information
"Our clinical approach prioritizes patient safety, individualized treatment planning, realistic expectations, and long-term follow-up throughout the international care journey."
About This Procedure
Why Choose Meva Clinic?
A non-surgical endoscopic procedure that temporarily slows stomach emptying and supports appetite control in eligible patients, as part of a nutrition plan.
Meva Clinic's non-surgical gastric botox coordination in Istanbul offers a comfortable outpatient pathway for appetite control and weight management. Specialist partners perform this endoscopic procedure under comfortable sedation, following a thorough medical assessment and BMI suitability evaluation. Depending on treatment planning, patients may also evaluate non-surgical options like the swallowable gastric balloon capsule, or surgical solutions including a gastric sleeve or gastric bypass surgery in Istanbul. During the session, botulinum toxin is precisely injected into targeted stomach muscle areas to temporarily slow digestion, prolonging the sensation of fullness. Every comprehensive coordination plan includes a short clinical observation period, private patient arrangements and structured nutritional guidance with regular follow-ups. Optional: a Bosphorus-view partner hotel can be arranged on request (separate cost).
Medically reviewed by
Op. Dr. Cuma A.
General Surgeon · Obesity & Metabolic Surgery
Graduate of Istanbul University–Cerrahpaşa Faculty of Medicine and specialist in general surgery. For more than 10 years his practice has focused on obesity and metabolic surgery — sleeve gastrectomy, gastric bypass, gastric botox and gastric balloon — with more than 10,000 bariatric procedures performed. Holds the Turkish Ministry of Health–approved obesity surgery certification.
Is This Treatment for Me?
Mild overweight
Appetite control issues
Non-surgical seekers
Comprehensive International Patient Care Plan
Private airport transfer according to the confirmed care plan
Optional: a Bosphorus-view partner hotel can be arranged on request (separate cost)
Dedicated patient support during the confirmed care pathway
Aftercare guidance or materials according to the confirmed treatment plan
Follow-up guidance according to individual medical recommendations
The Clinical Procedure
Endoscopic injection into the stomach wall.
Medical Assessment & BMI Review
Comprehensive evaluation of health history and BMI status to confirm treatment suitability.
Sedation & Endoscopic Prep
Administration of light sedation according to protocol to ensure a comfortable and safe experience.
Endoscopic Access
A thin, flexible endoscope is gently introduced through the mouth to inspect the stomach cavity.
Targeted Botox Injection
Precise injection of botulinum toxin into specific areas of the gastric muscle walls.
Observation & Recovery
A brief post-procedure monitoring period to ensure safety before same-day discharge.
Nutritional Coaching
Personalized dietary plans and appetite-control follow-up guidance to maximize results.
Recovery & Transformation Journey
Phase 1: Immediate
Clinical observation, short recovery under sedation, and same-day discharge.
Phase 2: Early Recovery
Immediate return to light daily activities, with transition to a customized liquid and soft-food diet.
Phase 3: Appetite Control
Appetite control effects stabilize as botox reduces gastric motility, promoting portion control.
Phase 4: Weight Management
Progress monitoring with ongoing dietary guidance and lifestyle support for sustainable results.
The Meva Advantage
Gastric Botox in Istanbul is a non-surgical endoscopic weight management option for suitable patients, usually performed as a short outpatient procedure with minimal downtime. Eligibility depends on BMI, eating habits, medical history and specialist assessment.
Medical Guidelines & Safety Protocols
Hospital-based procedures are coordinated through accredited partner hospitals, including JCI-accredited institutions where clinically appropriate. Below are the clinical guidelines, safety protocols, and medical reference documentation for this procedure.
Indicated / Suitable For
- Adults with mild overweight who mainly struggle with appetite control, early hunger or large portions, and want a non-surgical option.
- People who prefer a short endoscopic procedure under sedation, with no incision and no hospital night.
- Patients who accept that the effect is temporary, usually lasting a few months, and that the evidence for weight loss is still limited.
- Those ready to follow a guided liquid-to-soft-food transition and a structured nutrition plan, since diet is what drives most of the result.
- Candidates for whom a gastric balloon or surgery is not wanted or not yet indicated, after the options have been compared with the specialist.
Contraindications / Not Suitable
- Neuromuscular disorders such as myasthenia gravis, Lambert-Eaton syndrome or motor neurone disease, in which botulinum toxin can worsen muscle weakness.
- Pregnancy or breastfeeding, or a known allergy to botulinum toxin products.
- Previous stomach surgery, including bariatric operations, or an active stomach ulcer, gastrointestinal bleeding or known slow stomach emptying (gastroparesis).
- Current treatment with medicines that interact with botulinum toxin, such as aminoglycoside antibiotics, until reviewed by the physician.
- Heart, lung or airway conditions that make sedation unsafe, or an untreated eating disorder.
Pre-Operative Evaluation & Diagnostic Checks
Medical and Eating-Pattern Review: BMI, weight history, hunger pattern, current medication and previous treatments are reviewed, starting with the free online pre-assessment.
Blood Tests: Complete blood count, blood sugar or HbA1c, liver and kidney function and clotting where indicated, plus a pregnancy test for women.
Sedation Assessment: Heart, lung and airway fitness for sedation, an ECG where indicated, and clear fasting instructions for the procedure day.
Neuromuscular and Medication Check: Questions about muscle weakness, swallowing or vision problems and any interacting medicines, to confirm botulinum toxin can be used safely.
Endoscopic Inspection: At the start of the procedure the stomach lining is examined; if an ulcer or other finding is seen, the injection is postponed and the finding is managed first.
Potential Risks & Complications
In compliance with transparent clinical reporting, Meva Clinic ensures patients are fully informed of the physiological risks associated with surgical procedures through accredited partner-hospital safety protocols where clinically appropriate.
Drowsiness, a sore throat or brief nausea are common after sedation and pass within hours; oxygen levels and vital signs are monitored throughout, and you should not drive or sign important documents for the rest of that day.
Slower stomach emptying can cause bloating, early fullness, reflux or constipation, especially in the first weeks; the liquid-to-soft-food plan and small, slow meals keep this manageable.
Mild upper-abdominal discomfort or nausea for a day or two is possible after the injections and usually settles with simple medication.
Rarely, botulinum toxin can spread beyond the stomach and cause generalised weakness, swallowing difficulty or blurred vision; dosing and screening reduce this risk, and any such symptom needs prompt medical review.
Bleeding or perforation from the endoscope or injection needle are very rare; the procedure is carried out with direct camera control, and patients are told to report severe pain, black stools or vomiting blood.
Studies show mixed results, and some patients notice little change in appetite or weight; this is why the procedure is always combined with a nutrition plan and why other options may be discussed.
Realistic Expectations & Outcomes
Gastric botox aims to slow stomach emptying so that fullness lasts longer and smaller portions feel natural. It is worth being clear: research on its effect on weight is mixed and still limited. Some trials report a modest benefit when injections are combined with a structured diet, while others find little difference compared with placebo. The effect is temporary, usually a few months, because the stomach muscle gradually recovers. It does not remove stomach tissue and is not a substitute for bariatric surgery when obesity is more advanced. Any change in appetite is usually noticed within the first weeks, and progress is reviewed at around 3 and 6 months. No specific weight loss can be promised.
Revision & Follow-Up Policy
After you return home, your coordinator arranges remote nutrition reviews at about 1, 3 and 6 months to follow appetite, weight and any side effects. A repeat injection is considered only after the first effect has fully worn off and only if the first treatment was well tolerated and helpful, as judged individually by the specialist. If the response is limited, alternatives such as a gastric balloon or surgery can be discussed, without any automatic or free repeat procedure. For 12 months after your treatment you can also send photos to the medical team whenever you wish and receive their feedback, and your questions are answered remotely.
Authoritative Medical References & Studies
- [1]Theodoridis X, Chourdakis M, Haidich AB, Stamouli EM, Pagkalidou E, Fotiadou I, Talimtzi P, Gkaliagkousi E, Triantafyllou A. Treatment of obesity with intragastric injection of botulinum toxin. Is it worth the pinch? An overview of systematic reviews and meta-analysis. Obes Res Clin Pract. 2023;17(3):184-191.View Source
- [2]Yen YA, Wang CC, Sung WW, Fang KC, Huang SM, Lin CC, Tsai MC, Yang TW. Intragastric injection of botulinum toxin A for weight loss: A systematic review and meta-analysis of randomized controlled trials. J Gastroenterol Hepatol. 2022;37(6):983-992.View Source
- [3]Jung SH, Yoon JH, Choi HS, Nam SJ, Kim KO, Kim DH, Kim JW, Sohn W, Hyun YS, Park CH, Lee HL, et al. Comparative efficacy of bariatric endoscopic procedures in the treatment of morbid obesity: a systematic review and network meta-analysis. Endoscopy. 2020;52(11):940-954.View Source
Medical Disclaimer: This information about intragastric botulinum toxin injection is educational and does not replace a medical consultation. Its use for weight management is based on limited evidence, and eligibility, dose and sedation are decided by the specialist team. Seek urgent care for muscle weakness, difficulty swallowing or breathing, blurred vision, severe pain or vomiting blood.
Frequently Asked Questions
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Procedure Details
Hospital Stay
None
Hotel Package
Optional, on request
Return to Work
Immediate
Anaesthesia
Sedation